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In fact, the SELECT trial published in the New England Journal of Medicine found that weekly semaglutide reduced the risk of major cardiovascular death by 20% compared to placebo in adults with overweight or obesity and existing heart disease

Some slight bruising, redness, or inflammation around the injection site can occur

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The lack of diversity across trials that are modeling disease progression or assessing the efficacy of interventions can result in biased or inaccurate findings that have low external validity, or generalizability, and can further exacerbate existing disparities in AD/ADRD health outcomes